Elevated serum S-adenosylhomocysteine in cobalamin-deficient megaloblastic anemia
نویسندگان
چکیده
منابع مشابه
Megaloblastic Anemia in Pregnancy
MegalobJastic Anemia in Pregnancy Megaloblastic Anemia is one of The Rather Common Diseases of Pregnant Women Caused by Folic acid Deficiency The Disease Might Be Hazardous To affected Mothers and also Could be Fatal for foetus too. Megaloblastic Pregnant Women Will have Signs and Symptoms of This Disease mostly after 29th. Week of pregnancy. Adequate amount of Folate Will prevent Compli...
متن کاملCobalamin neuropathy. Is S-adenosylhomocysteine toxicity a factor?
Cobalamin neuropathy was produced in cape fruit bats (Rousettus aegyptiacus) by a cobalamin-free diet combined with intermittent exposure to nitrous oxide, which inactivates cobalamin. There were no significant differences in S-adenosylmethionine/S-adenosylhomocysteine ratios in the central nervous system of cobalamin-deficient and cobalamin-replete bats. Taken with other data there are no grou...
متن کاملMegaloblastic anaemia, cobalamin, and folate.
Developments relating to cobalamin and folate are reviewed. Current work on the relations between these two coenzymes are discussed, particularly those that have emerged in studies using nitrous oxide, which inactivates cobalamin.
متن کاملMegaloblastic anemia of pregnancy: characteristics of pure megaloblastic anemia and megaloblastic anemia associated with iron deficiency.
LTHOUGH megaboblastic anemia of pregnancy is considered mainly as a folic acid deficiency anemia, since this vitamin induces remission in most cases, its mechanism of production is still obscure. Dietary deficiency has been claimed to be the principal cause. However, this anemia has been observed in well-to-do women whose diet was satisfactory. Some other factors such as gastrointestinal upset,...
متن کاملOral versus intramuscular cobalamin treatment in megaloblastic anemia: a single-center, prospective, randomized, open-label study.
BACKGROUND Cobalamin (vitamin B12) deficiency, the most common cause of megaloblastic anemia, is treated with intramuscular (IM) cobalamin. It has been suggested by some investigators that oral (p.o.) cobalamin treatment may be as effective in the treatment of this condition, with the advantages of ease of administration and lower cost. OBJECTIVE This study assessed the effects and cost of p....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Metabolism
سال: 2007
ISSN: 0026-0495
DOI: 10.1016/j.metabol.2006.10.009